Oral crocetin administration suppressed refractive shift and axial elongation in a murine model of lens-induced myopia
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چکیده
منابع مشابه
Induction of axial eye elongation and myopic refractive shift in one-year-old chickens
Depriving the eyes of neonatal animals of form vision induces axial eye elongation and ipsilateral myopia. We studied one-year-old chickens, an age at which full body growth has been attained, to learn if form deprivation myopia can develop at a later stage. We found that ocular reactivity to visual form deprivation continues in one-year-old chickens; but both the growth stimulation and the myo...
متن کاملAmphiregulin Antibody and Reduction of Axial Elongation in Experimental Myopia
To examine the mechanism of ocular axial elongation in myopia, guinea pigs (age: 2-3weeks) which either underwent unilateral or bilateral lens-induced myopization (group 1) or which were primarily myopic at baseline (group 2) received unilateral intraocular injections of amphiregulin antibody (doses: 5, 10, or 15μg) three times in intervals of 9days. A third group of emmetropic guinea pigs got ...
متن کاملInfluence of overnight orthokeratology on axial elongation in childhood myopia.
PURPOSE This prospective study was conducted to assess the influence of overnight orthokeratology (OK) on axial elongation in children, with those wearing spectacles as controls. METHODS One hundred five subjects (210 eyes) were enrolled in the study. The OK group comprised 45 patients (90 eyes, age 12.1 ± 2.5 years, mean ± SD; OK group) who matched the inclusion criteria for OK. The control ...
متن کاملRefractive error, axial length, and relative peripheral refractive error before and after the onset of myopia.
PURPOSE To evaluate refractive error, axial length, and relative peripheral refractive error before, during the year of, and after the onset of myopia in children who became myopic compared with emmetropes. METHODS Subjects were 605 children 6 to 14 years of age who became myopic (at least -0.75 D in each meridian) and 374 emmetropic (between -0.25 D and +1.00 D in each meridian at all visits...
متن کاملRefractive lens exchange in high myopia: long term follow up.
AIM To establish long term outcomes and incidence of complications following refractive lens exchange (RLE) for the correction of high myopia. METHODS Operative and postoperative records of 62 cases of small incision phacoemulsification RLE performed in 37 patients over an 11 year period, by a single surgeon, were reviewed. In addition, patients were recalled for a follow up examination, whic...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2019
ISSN: 2045-2322
DOI: 10.1038/s41598-018-36576-w